Drug Standards
Sigma Aldrich Fine Chemicals Biosciences Clofibrate European Pharmacopoeia (EP) Reference Standard | 637-07-0 | MFCD00000615 |
Clofibrate European Pharmacopoeia (EP) Reference Standard | Mol Wt: 242.7 | 637-07-0 | MFCD00000615 |
Sigma Aldrich Fine Chemicals Biosciences Oxidronate for radiochemical purity testing European Pharmacopoeia (EP) Reference Standard | 14255-61-9 |
Oxidronate for radiochemical purity testing European Pharmacopoeia (EP) Reference Standard | Mol Wt: 235.97 | 14255-61-9 |
Apexbio Technology LLC Dibucaine 85-79-0 10mM (in 1mL DMSO)
Dibucaine (CAS 85-79-0) is an aminoamide local anesthetic known to inhibit rapid axonal transport of proteins In in vitro assays Dibucaine at 0 5 mM exhibited a level of transport blockade comparable to 1 mM tetracaine while 1 mM Dibucaine reduced radiolabeled protein accumulation at ligation sites by 92% and 0 5 mM by 72% These properties underline its utility in studies investigating the mechanisms underlying axonal transport and the effects of local anesthetics on neuronal function
Apexbio Technology LLC Atazanavir sulfate (BMS-232632-05) 229975-97-7 50mg
Atazanavir sulfate (BMS-232632-05) (CAS 229975-97-7) is a small-molecule inhibitor targeting HIV-1 protease It is designed to inhibit protease-mediated processing of HIV gag and gag-pol polyproteins thereby blocking viral particle maturation Atazanavir sulfate exerts its biological activity primarily through selective inhibition of HIV-1 protease In in vitro studies atazanavir sulfate demonstrates inhibitory activity against HIV-1 strains with reported IC50 values ranging from 2 to 5 nM Based on these pharmacological properties atazanavir sulfate holds research potential in antiviral studies focused on HIV replication mechanisms and investigations of drug metabolism mediated by hepatic CYP systems
Apexbio Technology LLC Salmeterol xinafoate 94749-08-3 50mg
Salmeterol xinafoate (CAS 94749-08-3) is a long-acting 2-adrenergic receptor agonist that induces smooth muscle relaxation leading to bronchodilation and vasodilation In vitro studies show that salmeterol reduces retinal M ller cell death by inhibiting IRS-1 (Ser307) phosphorylation implicating -adrenergic signaling in cell survival pathways In vivo experiments demonstrate that salmeterol suppresses pro-inflammatory cytokine production in allergen-stimulated murine models and attenuates inflammatory responses via modulation of dendritic cells Clinically salmeterol has been shown to enhance peak expiratory flow in asthma and is studied in combination therapies for persistent asthma supporting its utility in respiratory and immunological research
Cayman Chemical Montelukast sodium salt
A CysLT1 receptor antagonist (IC50 = 4.9 nM in HEK293 cell membranes expressing the human receptor); selective for CysLT1 over CysLT2 receptors (IC50 = >10,000 nM in COS-7 cell membranes expressing the human receptor); inhibits LTD4-induced bronchoconstriction in anesthetized guinea pigs (ED50 = 69 nmol/kg, p.o.); inhibits ovalbumin-induced airway hyperresponsiveness and increases in the number of total cells and eosinophils in BALF in a mouse model of allergic asthma at 3 and 10 mg/kg
Selleck Chemical LLC Oprozomib
Oprozomib is an orally bioavailable inhibitor for CT-L activity of 20S proteasome 5/LMP7 with IC50 of 36 nM/82 nM Phase 1/2
Medchemexpress LLC 1H-Benzimidazole, 6-bromo-4-fluoro-2-methyl-1-(1-methylethyl)- | 1231930-33-8 | >99.4% | C11H12BrFN2 | 100 G
Abemaciclib Impurity 1 is a high-purity chemical compound from MedChemExpress, available as an off-white to yellow solid. This impurity features the molecular formula C11H12BrFN2 and a molecular weight of 271.13. It is commonly used in chemical synthesis and research applications.
- Purity of >99.4%
- Storage as powder: -20°C for 3 years, or 4°C for 2 years
- Storage in solvent: -80°C for 6 months, or -20°C for 1 month
- Complies with specified quality standards
- Distinctive off-white to yellow solid appearance
Sigma Aldrich Fine Chemicals Biosciences Ketotifen impurity G European Pharmacopoeia (EP) Reference Standard | 43076-16-0 |
Ketotifen impurity G European Pharmacopoeia (EP) Reference Standard | Mol Wt: 323.41 | 43076-16-0 |
Medchemexpress LLC (rel)-Tivantinib ((rel)-ARQ 197) | 905853-99-8 | 96.45% | C23H19N3O2 | 50 MG
(rel)-Tivantinib, also known as (rel)-ARQ 197, is a potent and highly selective inhibitor of the receptor tyrosine kinase c-MET. This compound is known for its role in inhibiting cancer cell growth and proliferation by targeting the c-MET pathway, which is often dysregulated in various cancers. It has been investigated for its potential as an anti-cancer agent due to its ability to block c-MET signaling.
- Potent and highly selective c-MET inhibitor.
- Inhibits cancer cell growth and proliferation.
- Targets the c-MET signaling pathway.
- Investigated as a potential anti-cancer agent.
Sigma Aldrich Fine Chemicals Biosciences Ifosfamide impurity F European Pharmacopoeia (EP) Reference Standard | 40722-73-4 |
Ifosfamide impurity F European Pharmacopoeia (EP) Reference Standard | Mol Wt: 218.02 | 40722-73-4 |
Sigma Aldrich Fine Chemicals Biosciences Palonosetron Enantiomer United States Pharmacopeia (USP) Reference Standard | 135729-75-8 | 15MG
Palonosetron Enantiomer United States Pharmacopeia (USP) Reference Standard | Mol Wt: 332.87 | 135729-75-8 | 15MG
Sigma Aldrich Fine Chemicals Biosciences Interferon β-1a145258-61-3 | MFCD09702071 | 0.6mL
Interferon β-1a | 145258-61-3 | MFCD09702071 | 0.6mL
Cayman Chemical FlumazenIl-d5 2.5mg
An internal standard for the quantification of flumazenil by GC- or LC-MS